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When prescribing this medication your doctor will likely explain its use and may even provide a demonstration. It should also come with an instructional pamphlet included with the manufacturer’s packaging.

Before using this medication you will have to prime the device. You should do this when you first take the medication, if you haven’t used the inhaler in a few weeks, or if you drop it. To prime the Inhaler, shake the device well, point it away from you (to avoid getting medication) in your eyes and release a puff. Repeat this process three times.

Use the inhaler as instructed by your doctor. Do not use more than what is recommended as this will not accelerate treatment and may result in adverse side effects.

Once you have completed your doses rinse your mouth out with water to prevent irritation and infection. Do not swallow the rinse water. If you do require a second inhaler to manage symptoms, wait a full minute before taking a second inhaler.

Combivent Inhaler has known side effects. Before taking this medication it is important to consult with your doctor and be informed of the potential risks. Side effects can range from mild to serious. Mild side effects should be manageable and may even go away over time.
If you find that they become too bothersome, call your doctor or pharmacist to see if there is a way to mitigate them. If you experience serious side effects you may need to seek medical attention. These are not a complete list of potential side effects.

• sweating
• change in taste
• change in near or distance vision
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• difficulty with breathing
• blindness
• trembling or shaking of the hands or feet
• trouble sleeping
• swelling of the eye
• trouble swallowing
• Acid or sour stomach
• swelling or inflammation of the mouth
• muscle pain or stiffness
• dizziness
• welts
• sore throat
• tender, swollen glands in the neck
• frequent urge to urinate
• itching, redness, tearing, or other sign of eye irritation not present before use of this medicine or becoming worse during use
• lower back or side pain
• diarrhea
• bad, unusual, or unpleasant (after) taste
• difficulty with moving
• Bigger, dilated, or enlarged pupils (black part of the eye)
• voice changes
• noisy breathing
• itching skin
• cough
• unusual tiredness or weakness
• voice changes
• fever
• decreased vision
• chest pain
• pain
• loss of voice
• nausea
• diarrhea
• vomiting
• Skin rash or hives
• decrease in urine volume
• general feeling of discomfort or illness
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• noisy breathing
• swelling
• blurred vision
• nervousness
• bloody or cloudy urine
• lack or loss of strength
• runny nose
• pain or discomfort in the arms, jaw, back, or neck
• decrease in the frequency of urination
• shakiness in the legs, arms, hands, or feet
• swelling of the face, lips, eyelids, mouth, or throat
• eye pain
• Chest discomfort
• dry throat
• difficulty in passing urine (dribbling)
• chills
• burning while urinating burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• indigestion
• tightness in the chest
• tearing
• increased sputum
• joint pain
• Bladder pain
• Body aches or pain
• redness of the white part of the eyes or inside of the eyelids
• hoarseness
• sneezing
• stuffy nose
• dry mouth
• pounding in the ears
• belching
• heartburn
• redness of the skin
• cough producing mucus
• increased sensitivity of the eyes to light
• fast, slow, irregular, pounding, or racing heartbeat or pulse
• difficulty in focusing eyes
• ear congestion
• loss of appetite
• pain or tenderness around the eyes and cheekbones
• difficult, burning, or painful urination
• stomach discomfort, upset, or pain
• shivering
• headache
• fainting
• congestion
• muscle aches and pains

The following drugs are known to interact with Combivent Inhaler. This is not a complete list of all possible interactions. Be sure to disclose all your current medications to your doctor when discussing this medication so they can ensure this is safe to use and avoid allergic reactions. be sure to inform your doctor if you have high blood pressure, paradoxical bronchospasm, irregular heartbeat, narrow angle glaucoma or other serious medical conditions that may be life threatening.

• Amoxapine
• Levalbuterol
• Melitracen
• Amitriptyline
• Lofepramine
• Atomoxetine
• Methacholine
• Trimipramine
• Protriptyline
• Iobenguane I 123
• Amitriptylinoxide
• Scopolamine
• Nortriptyline
• Desipramine
• Opipramol
• Clozapine
• Tiotropium
• Doxepin
• Dibenzepin
• Imipramine
• Clomipramine
• Secretin Human
• Amineptine
• Revefenacin
• Tianeptine
• Glycopyrrolate
• Glycopyrronium Tosylate

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