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    What is Xeljanz?

    Xeljanz is a brand-name prescription medication for the treatment of certain types of arthritis (psoriatic arthritis and rheumatoid arthritis) and bowel diseases (ulcerative colitis). It belongs to a class of drugs called Janus kinase inhibitors which decrease the activity of the immune system. It comes as a tablet that’s taken by mouth. The active ingredient is tofacitinib, but it is only commercially available in its brand-name form.

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    Xeljanz Information

    Xeljanz dosage

    Xeljanz dosage will vary according to your doctor’s assessment. This evaluation may depend on the type or severity of your condition, age, and other medical conditions. It is available in strengths of 5 mg and 10 mg tablets.

    For rheumatoid arthritis and psoriatic arthritis, your dose is 5 mg twice daily. If you have moderate to severe kidney impairment and moderate liver impairment, the dosage will be 5 mg once daily. Take the tablets by mouth with or without food as directed by your doctor. For ulcerative colitis, the dose is prescribed at 10 mg twice daily for at least 8 weeks; then 5 mg twice daily.

    A dose of 10 mg can be continued for up to 16 weeks, depending on the person’s response to treatment. The dosage may be adjusted in those with moderate to severe liver impairment and moderate kidney impairment.

    How Xeljanz works

    Xeljanz is a Janus kinase inhibitor that helps disrupt pathways responsible for inflammation. It decreases a substance called cytokines, which are proteins in the body involved in inflammation.

    The body may release cytokines during inflammatory conditions like infections and autoimmune diseases. Patients with rheumatoid arthritis may produce more cytokines than usual, which can lead to inflammation and pain.

    What Xeljanz is used for

    Xeljanz is a Janus kinase inhibitor, it treats patients with moderate to severely active rheumatoid arthritis, active psoriatic arthritis, and moderate to severe active ulcerative colitis. It helps reduce symptoms of arthritis, such as pain, tenderness, and swelling in the joints.

    It also reduces symptoms of ulcerative colitis, which is a bowel disease. Symptoms of ulcerative colitis may include diarrhea, rectal bleeding, and stomach pain. Xeljanz is used to treat certain inflammatory conditions in people who’ve tried other drugs that were not effective enough or caused too many side effects.

    Before Xeljanz is prescribed

    Before taking Xeljanz, tell your doctor about all your medications. This includes prescription drugs, over-the-counter drugs, vitamins, and herbal products. Tell your doctor if you have a history of kidney disease, liver disease, blood disorders, infections, or other health conditions.

    Older adults may be at a greater risk of complications or adverse effects, especially infections, during treatment. Inform your doctor if you are pregnant or plan to become pregnant before your first dose. You should also tell your doctor if you are undergoing surgery before treatment. Take this regularly, as prescribed, to receive the maximum benefit.

    Xeljanz precautions and warnings

    Always read and understand the medication guide provided with the product before you begin taking treatment. When you buy Xeljanz online from Your Canada Drug Store, we always send the products in the manufacturer’s packaging.

    People taking Xeljanz may have an increased risk of adverse effects if they have a history of liver disease, kidney disease, blood or bone marrow disorders, infections, cancer, stomach or intestinal disorders, lung disease, heart disease, blood clots, or a history of stroke.

    The packaging has a black box warning for an increased risk of infections, lymphoma, and blood clots in the lungs, especially with high doses. Your doctor will evaluate the risk and benefits of treatment for your condition. Stop taking Xeljanz if you experience an allergic reaction and seek medical attention.

    It can especially make you more likely to get infections or worsen current infections, such as tuberculosis, invasive fungal infections, and bacterial or viral infections. Do not receive vaccinations while using this drug unless approved by your doctor.

    What are the side effects of Xeljanz?

    • Diarrhea
    • Headache
    • Upper respiratory infections
    • Rash
    • Increased cholesterol levels
    • High blood pressure

    Xeljanz carries warnings for serious side effects such as infections, cancer, and blood clots. Inform your doctor immediately if you experience any signs of these side effects.

    This is not a complete list of potential side effects. Report side effects to your doctor. If you find them unmanageable, call your doctor for medical advice about side effects. We also have a pharmacist that can provide counseling when you buy Xeljanz online.

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    Xeljanz FAQs

    Are Rinvoq and Xeljanz the same?

    Rinvoq is also a Janus kinase inhibitor, which treats moderate to severe rheumatoid arthritis. However, its generic name is upadacitinib. Rinvoq and Xeljanz come in different strengths and are prescribed in different doses.

    Who makes Xeljanz?

    Xeljanz is manufactured by Pfizer.

    Disclaimer: The information provided here is for informational purposes only and is not intended to replace the medical advice provided by a certified medical professional. You require your doctor's approval prior to buying or using Prescription Drugs sold here. We do have a pharmacist on staff if your doctor is unavailable to provide medical advice when you buy Xeljanz online. Do not use the information here to ignore or contradict advice provided by a licensed medical professional. Always seek medical advice if you have any questions or concerns about this medication.

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